Molecules, Free Full-Text

Human menin is a nuclear protein that participates in many cellular processes, as transcriptional regulation, DNA damage repair, cell signaling, cell division, proliferation, and migration, by interacting with many other proteins. Mutations of the gene encoding menin cause multiple endocrine neoplasia type 1 (MEN1), a rare autosomal dominant disorder associated with tumors of the endocrine glands. In order to characterize the structural and functional effects at protein level of the hundreds of missense variations, we investigated by computational methods the wild-type menin and more than 200 variants, predicting the amino acid variations that change secondary structure, solvent accessibility, salt-bridge and H-bond interactions, protein thermostability, and altering the capability to bind known protein interactors. The structural analyses are freely accessible online by means of a web interface that integrates also a 3D visualization of the structure of the wild-type and variant proteins. The results of the study offer insight into the effects of the amino acid variations in view of a more complete understanding of their pathological role.

NCERT Solutions Class 9 Science Chapter 3 Atoms And Molecules - Free Download

3D rendering molecule structure. Scientific medical background with atoms and molecules. Scientific animation for your banner, flyer, template, text. Molecule consists of atoms chemical element Stock Illustration

Molecules Background. Royalty-Free Stock Image - Storyblocks

Molecular biology animated word cloud, t, Stock Video

PDF] Molecules and Medicine by E. J. Corey eBook

Free Vector Structure molecule dna atom neurons scientific background for medicine science technology chemistry molecule illustration over blue background with copy space for your text

Time Evolution Of Polarized Optical Microscopy Morphology Of Pla And

Multi-modal molecule structure–text model for text-based retrieval and editing

Mean Free Path and Derivation of Mean Free Path - BYJU'S

Molecules: The Elements And The Architecture Of Everything : Theodore Gray, Nick Mann : Free Download, Borrow, and Streaming : Internet Archive