Advanced Quantitative Fluorescence Microscopy to Probe the Molecular Dynamics of Viral Entry, Science Lab

Viral entry into the host cell requires the coordination of many cellular and viral proteins in a precise order. Modern microscopy techniques are now allowing researchers to investigate these interactions with higher spatiotemporal resolution than ever before. Here we present two examples from the field of HIV research that make use of an innovative quantitative imaging approach as well as cutting edge fluorescence lifetime-based confocal microscopy methods to gain novel insights into how HIV fuses to cell membranes and enters the cell.

Understanding Virus Structure and Dynamics through Molecular Simulations

Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

Precision Fluorescent Labeling of an Adeno‐Associated Virus Vector to Monitor the Viral Infection Pathway - Zhang - 2018 - Biotechnology Journal - Wiley Online Library

Atomic force microscopy - Wikipedia

HIV-1 Vpr induces ciTRAN to prevent transcriptional repression of the provirus

Probing the interaction of influenza A viruses (IAVs) with cells and

Single-virus tracking with quantum dots in live cells

Ultrafast, sensitive, and portable detection of COVID-19 IgG using flexible organic electrochemical transistors

Viruses, Free Full-Text

Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection: Molecular Therapy

Microscopy in Virology, Science Lab

Viruses, Free Full-Text

Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition - ScienceDirect

CRISPR‐Cas Biochemistry and CRISPR‐Based Molecular Diagnostics - Weng - 2023 - Angewandte Chemie International Edition - Wiley Online Library

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