How does SARS-CoV-2 evade the immune defences?
Por um escritor misterioso
Last updated 11 abril 2025

As most of pathogens, SARS-CoV-2 can be recognized by pattern recognition receptors on innate. Normally, this recognition helps the innate immunity to eliminate the infection or to activate the adaptive immune responses, however, SARS-CoV-2 can use its proteins such as M, N, NSP1 and PLpro to interfere with these pathways.
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Immune evasion of SARS-CoV-2 from interferon antiviral system - ScienceDirect

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SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern - eBioMedicine

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

Virologica Sinica

Innate immune evasion strategies of SARS-CoV-2

Prevention of host-to-host transmission by SARS-CoV-2 vaccines - The Lancet Infectious Diseases
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