Relative Selectivity of Covalent Inhibitors Requires Assessment of Inactivation Kinetics and Cellular Occupancy: A Case Study of Ibrutinib and Acalabrutinib

Sigmoidal correlation between Btk occupancy and experimentally observed

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Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen

A Perspective on the Kinetics of Covalent and Irreversible Inhibition

Structure-Function Relationships of Covalent and Non-Covalent BTK Inhibitors. - Abstract - Europe PMC

BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies, Journal of Hematology & Oncology

A steady-state algebraic model for the time course of covalent enzyme inhibition

Case Study - COVALfinder to Study Irreversible EGFR Drugs

Case Study - COVALfinder to Study Irreversible EGFR Drugs